Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SREBF2 | Q12772 | 17/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | ATM | Q13315 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | SREBF1 | P36956 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4279310 | 0.85 | SREBF2 (0.72) | SREBF2MAPTATML3MBTL1ALDH1A1 | |
| SCHEMBL19887431 | 0.82 | SREBF2 (0.74) | SREBF2MAPTATML3MBTL1ALDH1A1 | |
| SCHEMBL4292767 | 0.82 | SREBF2 (1.00) | SREBF2MAPTATML3MBTL1ALDH1A1 | |
| SCHEMBL4284843 | 0.81 | SREBF2 (1.00) | SREBF2MAPTATML3MBTL1ALDH1A1 | |
| SCHEMBL15467920 | 0.81 | SREBF2 (0.69) | SREBF2MAPTATML3MBTL1ALDH1A1 | |
| SCHEMBL4283873 | 0.81 | SREBF2 (0.73) | SREBF2MAPTATML3MBTL1ALDH1A1 | |
| SCHEMBL4285116 | 0.79 | SREBF2 (1.00) | SREBF2MAPTATML3MBTL1ALDH1A1 | |
| SCHEMBL19733085 | 0.79 | SREBF2 (0.84) | SREBF2MAPTATML3MBTL1ALDH1A1 | |
| SCHEMBL4283881 | 0.79 | SREBF2 (1.00) | SREBF2MAPTATML3MBTL1ALDH1A1 | |
| SCHEMBL19887245 | 0.79 | SREBF2 (0.73) | SREBF2MAPTATML3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2120580-B1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF METABOLIC DISORDERS | BAYLOR COLLEGE MEDICINE (US) | 2017-12-27 | — | — | EP | claimed |