Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SREBF2 | Q12772 | 14/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | ATM | Q13315 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 2/20 | 0.41 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.41 |
| ▸ | SREBF1 | P36956 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19733086 | 0.91 | SREBF2 (0.55) | SREBF2MAPTATML3MBTL1KDM4E | |
| SCHEMBL4283901 | 0.85 | SREBF2 (0.58) | SREBF2MAPTATML3MBTL1KDM4E | |
| SCHEMBL4288916 | 0.82 | SREBF2 (0.55) | SREBF2MAPTATML3MBTL1KDM4E | |
| SCHEMBL4279577 | 0.80 | SREBF2 (0.53) | SREBF2MAPTATML3MBTL1KDM4E | |
| SCHEMBL4279440 | 0.76 | SREBF2 (0.57) | SREBF2MAPTATML3MBTL1KDM4E | |
| SCHEMBL4286484 | 0.76 | CDC7 (0.60) | SREBF2MAPTATML3MBTL1KDM4E | |
| SCHEMBL4286677 | 0.74 | SREBF2 (0.54) | SREBF2MAPTATML3MBTL1KDM4E | |
| SCHEMBL4286504 | 0.72 | SREBF2 (1.00) | SREBF2MAPTATML3MBTL1KDM4E | |
| SCHEMBL15953491 | 0.72 | SREBF2 (0.64) | SREBF2MAPTATML3MBTL1KDM4E | |
| SCHEMBL4293667 | 0.71 | SREBF2 (0.69) | SREBF2MAPTATML3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2120580-B1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF METABOLIC DISORDERS | BAYLOR COLLEGE MEDICINE (US) | 2017-12-27 | — | — | EP | claimed |