Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 19/20 | 1.00 |
| ▸ | KRAS | P01116 | 1/20 | 0.54 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19079348 | 0.89 | SMYD3 (0.80) | SMYD3KRASSOS1 | |
| SCHEMBL19079334 | 0.89 | SMYD3 (0.80) | SMYD3KRASSOS1 | |
| SCHEMBL19727303 | 0.88 | SMYD3 (0.79) | SMYD3 | |
| SCHEMBL19079347 | 0.87 | SMYD3 (0.78) | SMYD3 | |
| SCHEMBL19079333 | 0.87 | SMYD3 (0.78) | SMYD3 | |
| SCHEMBL19079337 | 0.87 | SMYD3 (0.76) | SMYD3SOS1 | |
| SCHEMBL19079332 | 0.87 | SMYD3 (0.76) | SMYD3SOS1 | |
| SCHEMBL19079385 | 0.85 | SMYD3 (0.73) | SMYD3 | |
| SCHEMBL19079364 | 0.85 | SMYD3 (0.73) | SMYD3 | |
| SCHEMBL19727305 | 0.83 | SMYD3 (1.00) | SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10577363-B2 | Substituted piperidine compounds | Epizyme, Inc. (US) | 2020-03-03 | — | — | US | disclosed |
| US-20170362217-A1 | Substituted Piperidine Compounds | Epizyme, Inc. (US) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10577363-B2 | Substituted piperidine compounds | SMYD3, SMYD2, SNRPD3 | SMYD3 1/4885KRAS 150/4885SOS1 2121/4885 |
| US-20170362217-A1 | Substituted Piperidine Compounds | SMYD3, SMYD2, SNRPD3 | SMYD3 1/4885KRAS 150/4885SOS1 2121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.