Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 17/20 | 0.61 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.61 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.61 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.61 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.61 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19734404 | 1.00 | SCN9A (0.61) | SCN9ASCN7ASCN5ASCN2ASCN8A | |
| SCHEMBL19734464 | 0.88 | SCN9A (0.65) | SCN9ASCN7ASCN5ASCN2ASCN8A | |
| SCHEMBL15312938 | 0.88 | SCN9A (0.65) | SCN9ASCN7ASCN5ASCN2ASCN8A | |
| SCHEMBL19763103 | 0.87 | SCN9A (0.64) | SCN9ASCN7ASCN5ASCN2ASCN8A | |
| SCHEMBL19763101 | 0.87 | SCN9A (0.64) | SCN9ASCN7ASCN5ASCN2ASCN8A | |
| SCHEMBL19734522 | 0.84 | SCN9A (0.60) | SCN9ASCN7ASCN5ASCN2ASCN8A | |
| SCHEMBL19734523 | 0.84 | SCN9A (0.60) | SCN9ASCN7ASCN5ASCN2ASCN8A | |
| SCHEMBL19734405 | 0.82 | SCN9A (0.58) | SCN9ASCN7ASCN5ASCN2ASCN8A | |
| SCHEMBL19734400 | 0.82 | SCN9A (0.58) | SCN9ASCN7ASCN5ASCN2ASCN8A | |
| SCHEMBL15314972 | 0.79 | SCN9A (0.65) | SCN9ASCN7ASCN5ASCN2ASCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017218920-A1 | ASYMMETRIC SYNTHESIS OF FUNAPIDE | TEVA PHARMACEUTICALS INTERNATIONAL GMBH (CH) | 2017-12-21 | — | — | WO | disclosed |