SCHEMBL1973686

SCHEMBL1973686

CC(C)C1c2nc[nH]c2CCN1C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 3/20 0.65
RAB9A P51151 1/20 0.35
KDM4E B2RXH2 3/20 0.32
ALDH1A1 P00352 2/20 0.32
GAA P10253 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
POLB P06746 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12094922 1.00 AOC3 (0.65) AOC3RAB9AKDM4EALDH1A1GAA
Hydrochloric Acid SCHEMBL18173566 0.99 AOC3 (0.64) AOC3RAB9AKDM4EALDH1A1GAA
Phosphoric Acid SCHEMBL18173592 0.95 AOC3 (0.60) AOC3RAB9AKDM4EALDH1A1GAA
Sulfuric Acid SCHEMBL18173563 0.94 AOC3 (0.59) AOC3RAB9A
SCHEMBL18173571 0.94 AOC3 (0.59) AOC3RAB9A
SCHEMBL11516578 0.85 AOC3 (0.58) AOC3RAB9ASMN1; SMN2
SCHEMBL1976869 0.82 AOC3 (0.64) AOC3ALDH1A1POLB
SCHEMBL18953107 0.81 AOC3 (0.62) AOC3ALDH1A1POLB
SCHEMBL10325666 0.81 AOC3 (0.47) AOC3RAB9AKDM4EALDH1A1GAA
SCHEMBL11514454 0.80 AOC3 (0.53) AOC3RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010031789-A1 NEW COMPOUNDS I BIOVITRUM AB (PUBL) (SE) 2010-03-25 WO claimed
EP-3386494-A1 VAP-1 INHIBITORS FOR TREATING PAIN Benevolentai Cambridge Limited (GB) 2018-10-17 EP disclosed
WO-2017098236-A1 VAP-1 INHIBITORS FOR TREATING PAIN PROXIMAGEN LIMITED (GB) 2017-06-15 WO disclosed
EP-2334672-A1 NEW COMPOUNDS I Proximagen Limited (GB) 2011-06-22 EP disclosed
WO-2010031789-A1 NEW COMPOUNDS I BIOVITRUM AB (PUBL) (SE) 2010-03-25 WO disclosed