Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 3/20 | 0.77 |
| ▸ | MINK1 | Q8N4C8 | 3/20 | 0.77 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.77 |
| ▸ | MARK3 | P27448 | 2/20 | 0.77 |
| ▸ | PLK1 | P53350 | 2/20 | 0.77 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.77 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.61 |
| ▸ | PIM1 | P11309 | 1/20 | 0.61 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.61 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.61 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.61 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.61 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.61 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.61 |
| ▸ | S1PR1 | P21453 | 17/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1974124 | 1.00 | MAP4K4 (0.77) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| SCHEMBL2345614 | 1.00 | MAP4K4 (0.77) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| SCHEMBL1974131 | 1.00 | MAP4K4 (0.77) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| SCHEMBL2338187 | 0.91 | MAP4K4 (0.84) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| SCHEMBL2340753 | 0.89 | MAP4K4 (0.82) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| SCHEMBL2340158 | 0.89 | MAP4K4 (0.83) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| SCHEMBL2341721 | 0.89 | MAP4K4 (0.81) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| SCHEMBL2339449 | 0.88 | MAP4K4 (0.79) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| SCHEMBL3746206 | 0.87 | MAP4K4 (1.00) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| SCHEMBL12391386 | 0.87 | MAP4K4 (1.00) | MAP4K4MINK1DYRK3MARK3PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011071570-A1 | NOVEL OXADIAZOLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-16 | — | — | WO | disclosed |