SCHEMBL19741573

SCHEMBL19741573

C=CCCCCCCc1ccc2c(c1)CC2

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 2/20 0.40
USP2 O75604 1/20 0.40
ALDH1A1 P00352 1/20 0.40
HPGD P15428 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
HDAC4 P56524 1/20 0.39
GRIN2B Q13224 2/20 0.35
CDK1 P06493 1/20 0.34
IGF1R P08069 1/20 0.33
ALOX15 P16050 1/20 0.33
ADRA2A P08913 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
MLNR O43193 1/20 0.33
S1PR1 P21453 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8527146 0.85 HDAC1 (0.39) HDAC1USP2ALDH1A1HPGDTDP1
SCHEMBL12794975 0.79 S1PR1 (0.32) GRIN2BS1PR1
SCHEMBL11336193 0.79 TDP1 (0.52) HDAC1USP2ALDH1A1HPGDTDP1
SCHEMBL12989712 0.79 TDP1 (0.52) HDAC1USP2ALDH1A1HPGDTDP1
SCHEMBL7693217 0.78 CDK1 (0.40) ALDH1A1HPGDTDP1GRIN2BCDK1
SCHEMBL11328438 0.77 TDP1 (0.48) HDAC1USP2ALDH1A1HPGDTDP1
SCHEMBL19996369 0.77 SLC6A2 (0.50) ALDH1A1ADRA2AADRA2BADRA2CMLNR
SCHEMBL12379609 0.77 GRIN2B (0.38) GRIN2BCDK1IGF1RALOX15MLNR
SCHEMBL16682975 0.77 GRIN2B (0.38) GRIN2BCDK1IGF1RALOX15MLNR
SCHEMBL19668939 0.77 GRIN2B (0.38) GRIN2BCDK1IGF1RALOX15MLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3237467-B1 ETHYLENE-BASED INTERPOLYMERS AND COMPOSITION COMPRISING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2024-05-22 EP disclosed
US-10160817-B2 Ethylene based interpolymers and composition comprising the same DOW GLOBAL TECHNOLOGIES LLC (US) 2018-12-25 US disclosed
US-20170369609-A1 Ethylene-Based Interpolymers and Composition Comprising the Same DOW GLOBAL TECHNOLOGIES LLC 2017-12-28 US disclosed