Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.56 |
| ▸ | KDM5C | P41229 | 2/20 | 0.56 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | WNT1 | P04628 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 4/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17144722 | 0.98 | KDM4C (0.56) | KDM4CKDM5CKDM2BCYP2D6CYP2C9 | |
| SCHEMBL17144777 | 0.93 | KDM4C (0.58) | KDM4CKDM5CKDM2BWNT1DYRK1A | |
| SCHEMBL17144910 | 0.87 | JMJD6 (0.42) | KDM4CKDM5CWNT1DYRK1AJMJD6 | |
| SCHEMBL2305288 | 0.84 | KDM4C (0.76) | KDM4CKDM5CKDM2BCYP2D6CYP2C9 | |
| SCHEMBL17145118 | 0.83 | JMJD6 (0.46) | KDM4CKDM5CWNT1DYRK1AJMJD6 | |
| SCHEMBL16291774 | 0.82 | KDM4C (0.74) | KDM4CKDM5CKDM2BCYP2D6CYP2C9 | |
| SCHEMBL15636461 | 0.81 | KDM4C (0.76) | KDM4CKDM5CKDM2BCYP2D6CYP2C9 | |
| SCHEMBL17144820 | 0.80 | CXCR4 (0.41) | KDM4CKDM5CSCDSCD5VNN1 | |
| SCHEMBL17145009 | 0.78 | CXCR4 (0.35) | KDM4CKDM5CSCDSCD5 | |
| SCHEMBL21257752 | 0.75 | KDM4C (0.54) | KDM4CKDM5CKDM2BCYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170369444-A1 | INHIBITORS OF HISTONE DEMETHYLASES | EPITHERAPEUTICS APS (DK) | 2017-12-28 | — | — | US | claimed |
| US-20170369444-A1 | INHIBITORS OF HISTONE DEMETHYLASES | EPITHERAPEUTICS APS (DK) | 2017-12-28 | — | — | US | disclosed |
| US-20170369444-A1 | INHIBITORS OF HISTONE DEMETHYLASES | EPITHERAPEUTICS APS (DK) | 2017-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170369444-A1 | INHIBITORS OF HISTONE DEMETHYLASES | KDM1B, KDM3A, KDM1A | KDM4C 38/4885KDM5C 16/4885KDM2B 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.