Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15060 | 1.00 | — | — | |
| SCHEMBL991896 | 0.95 | — | — | |
| SCHEMBL10611388 | 0.95 | — | — | |
| SCHEMBL3852332 | 0.95 | — | — | |
| SCHEMBL3290029 | 0.95 | — | — | |
| Ammonia Solution, Strong SCHEMBL4804798 | 0.95 | — | — | |
| Methane SCHEMBL5460275 | 0.95 | — | — | |
| Ammonia Solution, Strong SCHEMBL3702957 | 0.95 | TSHR (0.50) | TSHRTP53ALDH1A1LMNATHRB | |
| SCHEMBL3741326 | 0.95 | — | — | |
| SCHEMBL28085934 | 0.95 | TSHR (0.50) | TSHRTP53ALDH1A1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078416-A1 | ORTHOGONAL METABOLIC FRAMEWORK FOR ONE-CARBON UTILIZATION | MOJIA BIOTECH PTE LTD (SG) | 2026-03-19 | — | — | US | disclosed |
| EP-4388104-A2 | ORTHOGONAL METABOLIC FRAMEWORK FOR ONE-CARBON UTILIZATION | Mojia Biotech Pte. Ltd. (SG) | 2024-06-26 | — | — | EP | disclosed |
| WO-2023023097-A2 | ORTHOGONAL METABOLIC FRAMEWORK FOR ONE-CARBON UTILIZATION | UNIVERSITY OF SOUTH FLORIDA (US) | 2023-02-23 | — | — | WO | disclosed |
| US-20170370954-A1 | Biomarkers for Fatty Liver Disease and Methods Using the Same | METABOLON, INC. | 2017-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078416-A1 | ORTHOGONAL METABOLIC FRAMEWORK FOR ONE-CARBON UTILIZATION | COASY, HACL2, ACSL1 | TSHR 3438/4885TP53 4768/4885ALDH1A1 284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.