SCHEMBL19743377

SCHEMBL19743377

FC(F)(c1ccccc1)c1nc(N2CC[C@H](N=C=S)C2)c2nnn(Cc3ccccc3Cl)c2n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 20/20 1.00
CNR1 P21554 8/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19743410 1.00 CNR2 (1.00) CNR2CNR1
SCHEMBL29848629 1.00 CNR2 (1.00) CNR2CNR1
SCHEMBL29848578 0.89 CNR2 (1.00) CNR2CNR1
SCHEMBL19744096 0.89 CNR2 (1.00) CNR2CNR1
SCHEMBL19744026 0.88 CNR2 (1.00) CNR2CNR1
SCHEMBL29848594 0.88 CNR2 (1.00) CNR2CNR1
SCHEMBL20968359 0.85 CNR2 (0.75) CNR2CNR1
SCHEMBL19743390 0.83 CNR2 (1.00) CNR2CNR1
SCHEMBL20968249 0.83 CNR2 (0.79) CNR2CNR1
SCHEMBL30298870 0.82 CNR2 (1.00) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3475282-A1 [1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES WITH AFFINITY FOR THE TYPE-2 CANNABINOID RECEPTOR H. Hoffnabb-La Roche Ag (CH) 2019-05-01 EP disclosed
WO-2017220517-A1 [1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES WITH AFFINITY FOR THE TYPE-2 CANNABINOID RECEPTOR F. HOFFMANN-LA ROCHE AG (CH) 2017-12-28 WO disclosed