SCHEMBL19743412

SCHEMBL19743412

Cc1nonc1Cn1nnc2c(N3C[CH]CC3)nc(C(C)(C)C)nc21

nearest known ligand 0.73

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 20/20 0.73
CNR1 P21554 2/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28688747 0.86 CNR2 (0.78) CNR2CNR1
SCHEMBL19743340 0.85 CNR2 (1.00) CNR2CNR1
SCHEMBL14911586 0.82 CNR2 (0.73) CNR2CNR1
SCHEMBL19743374 0.81 CNR2 (1.00) CNR2CNR1
SCHEMBL14911295 0.81 CNR2 (0.80) CNR2CNR1
SCHEMBL30298833 0.81 CNR2 (1.00) CNR2CNR1
SCHEMBL19743997 0.81 CNR2 (1.00) CNR2CNR1
SCHEMBL14911292 0.81 CNR2 (0.80) CNR2CNR1
SCHEMBL14912112 0.81 CNR2 (0.80) CNR2CNR1
SCHEMBL30298815 0.81 CNR2 (1.00) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3475282-A1 [1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES WITH AFFINITY FOR THE TYPE-2 CANNABINOID RECEPTOR H. Hoffnabb-La Roche Ag (CH) 2019-05-01 EP disclosed
WO-2017220517-A1 [1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES WITH AFFINITY FOR THE TYPE-2 CANNABINOID RECEPTOR F. HOFFMANN-LA ROCHE AG (CH) 2017-12-28 WO disclosed