SCHEMBL19743518

SCHEMBL19743518

CC(=O)/C1=C/C/C=C\CC/C=C\CCC1

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 2/20 0.37
HDAC2 Q92769 2/20 0.37
HDAC8 Q9BY41 2/20 0.37
HDAC6 Q9UBN7 2/20 0.37
HDAC3 O15379 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC5 Q9UQL6 1/20 0.37
CTSK P43235 1/20 0.33
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19743514 1.00 HDAC4 (0.37) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL19743516 1.00 HDAC4 (0.37) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL720598 0.79
Water SCHEMBL27869127 0.77
SCHEMBL19743890 0.75 HDAC4 (0.33) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL21051555 0.75 HDAC4 (0.33) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL19743889 0.75 HDAC4 (0.33) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL21051557 0.75 HDAC4 (0.33) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL19743464 0.75 HDAC4 (0.33) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL19743892 0.75 HDAC4 (0.33) HDAC4HDAC2HDAC8HDAC6HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3475401-A1 POWERFUL WOODY POWDERY ODORANT Firmenich S.A. (CH) 2019-05-01 EP disclosed
WO-2017220568-A1 POWERFUL WOODY POWDERY ODORANT FIRMENICH SA (CH) 2017-12-28 WO disclosed