Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 18/20 | 0.57 |
| ▸ | CNR1 | P21554 | 4/20 | 0.50 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19744182 | 0.89 | CNR2 (0.53) | CNR2CNR1RAD51KMT2A | |
| SCHEMBL19743555 | 0.88 | CNR2 (0.65) | CNR2CNR1 | |
| SCHEMBL19743667 | 0.73 | CNR2 (0.44) | CNR2CNR1 | |
| SCHEMBL19743556 | 0.73 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL17731800 | 0.72 | CNR2 (0.62) | CNR2CNR1 | |
| SCHEMBL19743563 | 0.72 | RAD51 (0.44) | CNR2RAD51KMT2A | |
| SCHEMBL28688747 | 0.72 | CNR2 (0.78) | CNR2CNR1 | |
| SCHEMBL19743579 | 0.70 | CNR2 (0.49) | CNR2RAD51KMT2A | |
| SCHEMBL19743982 | 0.70 | CNR2 (0.78) | CNR2CNR1 | |
| SCHEMBL21860773 | 0.69 | CNR2 (0.39) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3475282-A1 | [1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES WITH AFFINITY FOR THE TYPE-2 CANNABINOID RECEPTOR | H. Hoffnabb-La Roche Ag (CH) | 2019-05-01 | — | — | EP | disclosed |
| WO-2017220517-A1 | [1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES WITH AFFINITY FOR THE TYPE-2 CANNABINOID RECEPTOR | F. HOFFMANN-LA ROCHE AG (CH) | 2017-12-28 | — | — | WO | disclosed |