SCHEMBL1974475

SCHEMBL1974475

CC(C)(C)OC(=O)CCc1ccc(O)cc1C(C)(C)C

nearest known ligand 0.74

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NR1I2 O75469 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
CYP2C9 P11712 1/20 0.42
MIF P14174 1/20 0.42
TYR P14679 1/20 0.42
ALOX15 P16050 1/20 0.42
HTT P42858 1/20 0.42
NFE2L2 Q16236 1/20 0.42
HSD17B10 Q99714 1/20 0.42
NQO2 P16083 1/20 0.39
HTR6 P50406 1/20 0.38
EGFR P00533 1/20 0.37
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27829073 0.91 EGFR (0.40) NR1I2ALDH1A1LMNACYP2C9MIF
SCHEMBL7157589 0.87 MIF (0.43) NR1I2ALDH1A1LMNACYP2C9MIF
SCHEMBL22032600 0.85 TYR (0.52) TYR
SCHEMBL14110319 0.84 EGFR (0.40) NQO2HTR6EGFRPOLB
SCHEMBL4678556 0.84 NQO2 (0.40) NQO2HTR6EGFR
SCHEMBL16355739 0.82 NQO2 (0.39) NQO2HTR6EGFR
SCHEMBL740968 0.81 POLB (0.50) NR1I2ALDH1A1LMNACYP2C9MIF
SCHEMBL14110470 0.81 CHRNA7 (0.40) NQO2HTR6EGFRPOLB
SCHEMBL14369985 0.81 EGFR (0.39) NQO2HTR6EGFRPOLB
SCHEMBL3683721 0.81 EGFR (0.39) NQO2HTR6EGFRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110300778-A Composition having thermal conductivity and laser-plating properties by means of core-shell structured LDS additives with metal compounds coated on the surface of mineral fillers 沙特基础工业全球技术公司 2019-10-01 CN disclosed
CN-110268013-A Laser-platable thermoplastic composition with laser-activatable metal compound and shaped article thereof 沙特基础工业全球技术公司 2019-09-20 CN disclosed
CN-110016727-A Ultra-high molecular weight polyethylene powder and ultra high molecular weight polyethylene fiber 旭化成株式会社 2019-07-16 CN disclosed
CN-106604967-B Flame-retarded heat-conducting polymer composition with good flowability characteristics and application thereof 沙特基础工业全球技术公司 2019-07-16 CN disclosed
CN-109912881-A The polyolefine resin composition for being used to coat cable comprising xenogenesis rubber constituent 韩华道达尔有限公司 2019-06-21 CN disclosed
CN-109562542-A The polycarbonate Alloys of high demolding performace 沙特基础工业全球技术有限公司 2019-04-02 CN disclosed
CN-105264011-B Polymer composition, preparation method and the product formed by it 沙特基础全球技术有限公司 2019-01-11 CN disclosed
CN-106604967-A Flame retardant thermally conductive polymer compositions with good flow property and uses thereof 沙特基础工业全球技术公司 2017-04-26 CN disclosed
CN-104937025-B Polyethylene blend compositions and films 诺瓦化学品(国际)股份有限公司 2017-03-15 CN disclosed
CN-106467715-A The chip processing manufacture method of adhesivess, wafer layer stack and slim chip 信越化学工业株式会社 2017-03-01 CN disclosed
EP-2512543-A1 HYDROPHILIC COATING C.R. Bard Inc. (US) 2012-10-24 EP disclosed
US-8287890-B2 Hydrophilic coating C.R. BARD, INC. (US) 2012-10-16 US disclosed
WO-2011081908-A1 HYDROPHILIC COATING C.R. BARD, INC. (US) 2011-07-07 WO disclosed
US-20110144579-A1 HYDROPHILIC COATING C.R. BARD, INC. 2011-06-16 US disclosed
CN-1194021-C transparent polystyrene resin QIMEI IND CO LTD (CN) 2005-03-23 CN disclosed
CN-1336389-A transparent polystyrene resin QIMEI IND CO LTD (CN) 2002-02-20 CN disclosed
EP-0895606-A4 COATED OPTICAL FIBERS HAVING A REDUCED CONTENT OF EXTRACTABLE AND VOLATILE MATERIAL BORDEN CHEM INC (US) 2000-12-06 EP disclosed
EP-0895606-A1 COATED OPTICAL FIBERS HAVING A REDUCED CONTENT OF EXTRACTABLE AND VOLATILE MATERIAL BORDEN CHEMICAL, INC. (US) 1999-02-10 EP disclosed
WO-1998019189-A1 COATED OPTICAL FIBERS HAVING A REDUCED CONTENT OF EXTRACTABLE AND VOLATILE MATERIAL BORDEN CHEMICAL, INC. (US) 1998-05-07 WO disclosed
US-5179174-A Flexible lubricious organic coatings C. R. BARD, INC. (US) 1993-01-12 US disclosed