Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 19/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 15/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19746498 | 0.92 | HDAC6 (0.50) | HDAC6HDAC1HDAC8HDAC5HDAC4 | |
| SCHEMBL19746960 | 0.88 | HDAC6 (0.52) | HDAC6HDAC1HDAC8HDAC5HDAC4 | |
| SCHEMBL19746092 | 0.88 | HDAC6 (0.46) | HDAC6HDAC1HDAC8HDAC5HDAC4 | |
| SCHEMBL19746870 | 0.87 | HDAC6 (0.48) | HDAC6HDAC1HDAC8HDAC5HDAC4 | |
| SCHEMBL19746215 | 0.87 | HDAC6 (0.51) | HDAC6HDAC1HDAC8HDAC5HDAC4 | |
| SCHEMBL19746301 | 0.86 | HDAC6 (0.48) | HDAC6HDAC1HDAC8HDAC5HDAC4 | |
| SCHEMBL19747196 | 0.86 | HDAC6 (0.53) | HDAC6HDAC1HDAC8HDAC5HDAC4 | |
| SCHEMBL19746970 | 0.85 | HDAC6 (0.52) | HDAC6HDAC1HDAC8HDAC5HDAC4 | |
| SCHEMBL19746376 | 0.84 | HDAC6 (0.50) | HDAC6HDAC1HDAC8HDAC5HDAC4 | |
| SCHEMBL19745968 | 0.83 | HDAC6 (0.46) | HDAC6HDAC1HDAC8HDAC5HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017222952-A1 | 3- HETEROARYL SUBSTITUTED 5-TRIFLUOROMETHYL OXADIAZOLES AS HISTONE DEACETYLASE 6 (HDAC6) INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2017-12-28 | — | — | WO | claimed |
| US-11708358-B2 | Fungicidal oxadiazoles | FMC CORPORATION (US) | 2023-07-25 | — | — | US | disclosed |
| US-11708358-B2 | Fungicidal oxadiazoles | FMC CORPORATION (US) | 2023-07-25 | — | — | US | disclosed |
| US-20200148672-A1 | FUNGICIDAL OXADIAZOLES | FMC CORPORATION | 2020-05-14 | — | — | US | disclosed |
| WO-2017222952-A1 | 3- HETEROARYL SUBSTITUTED 5-TRIFLUOROMETHYL OXADIAZOLES AS HISTONE DEACETYLASE 6 (HDAC6) INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2017-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200148672-A1 | FUNGICIDAL OXADIAZOLES | OXA1L, NOX1, TH | HDAC6 1038/4885HDAC1 1586/4885HDAC8 2957/4885 |
| US-11708358-B2 | Fungicidal oxadiazoles | OXA1L, NOX1, TH | HDAC6 1038/4885HDAC1 1586/4885HDAC8 2957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.