Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28226960 | 0.88 | NOTUM (0.50) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL21823912 | 0.76 | NOTUM (0.71) | LMNAMAPTALDH1A1KMT2ASMN1; SMN2 | |
| Pyridine SCHEMBL28721033 | 0.76 | TSHR (0.50) | LMNAALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL27932462 | 0.73 | — | — | |
| SCHEMBL10186929 | 0.73 | — | — | |
| SCHEMBL470271 | 0.73 | — | — | |
| SCHEMBL15314435 | 0.67 | — | — | |
| SCHEMBL9728 | 0.65 | MAPT (1.00) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10000032 | 0.62 | MAPT (0.92) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL135626 | 0.62 | MAPT (0.92) | LMNAMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200249172-A1 | Colorimetric Detection of Organic Amines Using Metal-Organic Frameworks | THE JOHNS HOPKINS UNIVERSITY | 2020-08-06 | — | — | US | disclosed |
| US-9848599-B2 | Co-crystals of 3-iodopropynyl butylcarbamate | POLITECNICO DI MILANO (IT) | 2017-12-26 | — | — | US | disclosed |