⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3344209 | 1.00 | — | — | |
| SCHEMBL3340339 | 1.00 | — | — | |
| SCHEMBL197424 | 0.81 | — | — | |
| SCHEMBL1201554 | 0.81 | — | — | |
| SCHEMBL1201578 | 0.81 | — | — | |
| SCHEMBL4447672 | 0.79 | — | — | |
| SCHEMBL74345 | 0.79 | — | — | |
| SCHEMBL6264045 | 0.79 | — | — | |
| SCHEMBL4524525 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL28179334 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 947 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145505-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | ACRIVON THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | claimed |
| US-20230143583-A1 | AMIDE COMPOUNDS AS KINASE INHIBITORS, COMPOSITIONS AND METHODS OF TREATMENT | TRANSLATIONAL DRUG DEVELOPMENT, LLC | 2023-05-11 | — | — | US | claimed |
| CN-115803025-A | Non-lysosomal glucosylceramidase inhibitors and uses thereof | 阿勒克图治疗公司 | 2023-03-14 | — | — | CN | claimed |
| CN-115160295-A | Amide compounds as kinase inhibitors | 转化药物开发有限责任公司 | 2022-10-11 | — | — | CN | claimed |
| US-11001564-B2 | Substituted chromane-8-carboxamide compounds and analogues thereof, and methods using same | ARBUTUS BIOPHARMA CORPORATION (CA) | 2021-05-11 | — | — | US | claimed |
| EP-3784226-A1 | AMIDE COMPOUNDS AS KINASE INHIBITORS, COMPOSITIONS AND METHODS OF TREATMENT | TRANSLATIONAL DRUG DEVELOPMENT LLC (US) | 2021-03-03 | — | — | EP | claimed |
| CN-112367982-A | Amide compounds as kinase inhibitors, compositions and methods of treatment | 转化药物开发有限责任公司 | 2021-02-12 | — | — | CN | claimed |
| US-10738007-B2 | Amide compounds as kinase inhibitors, compositions and methods of treatment | Translation Drug Development, LLC (US) | 2020-08-11 | — | — | US | claimed |
| EP-3639824-A1 | TRICYCLIC NITROGEN CONTAINING COMPOUNDS FOR TREATING NEISSERIA GONORRHOEA INFECTION | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2020-04-22 | — | — | EP | claimed |
| US-20190248744-A1 | AMIDE COMPOUNDS AS KINASE INHIBITORS, COMPOSITIONS AND METHODS OF TREATMENT | TRANSLATIONAL DRUG DEVELOPMENT, LLC | 2019-08-15 | — | — | US | claimed |
| US-5705498-A | Piperidine derivatives as 5-HT4 receptor antagonists | SMITHKLINE BEECHAM PLC. (GB) | 1998-01-06 | — | — | US | claimed |
| EP-0521827-B1 | Pharmacological active hydrazin derivatives and process for their preparation | CIBA GEIGY AG (CH) | 1996-09-25 | — | — | EP | claimed |
| CN-1126472-A | 5-HT4 receptor antagonists | SMITHKLINE BEECHAM PLC (GB) | 1996-07-10 | — | — | CN | claimed |
| EP-0699194-A1 | 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-03-06 | — | — | EP | claimed |
| EP-0684947-A1 | AMIDE COMPOUNDS WITH PHARMACOLOGICAL ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1995-12-06 | — | — | EP | claimed |
| EP-0667867-A1 | PIPERIDINE DERIVATIVES AS 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-08-23 | — | — | EP | claimed |
| WO-1994027987-A1 | 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-12-08 | — | — | WO | claimed |
| CN-1092422-A | Medicine | SMITHKLINE BEECHAM PLC (GB) | 1994-09-21 | — | — | CN | claimed |
| WO-1994019344-A1 | AMIDE COMPOUNDS WITH PHARMACOLOGICAL ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1994-09-01 | — | — | WO | claimed |
| WO-1994010174-A1 | PIPERIDINE DERIVATIVES AS 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-05-11 | — | — | WO | claimed |