SCHEMBL197519

SCHEMBL197519

CCCCC(CC)COC(=O)CCCCCCCCC(=O)OCC(CC)CCCC.CCCCC(CC)COC(=O)CCCCCCCCC(=O)OCC(CC)CCCC

nearest known ligand 0.96

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.96
CYP3A4 P08684 2/20 0.96
ATM Q13315 1/20 0.96
TDP1 Q9NUW8 1/20 0.96
LMNA P02545 2/20 0.62
ALDH1A1 P00352 2/20 0.62
RECQL P46063 1/20 0.59
MAPT P10636 1/20 0.59
KDM4E B2RXH2 1/20 0.56
DUSP3 P51452 1/20 0.56
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
CA2 P00918 1/20 0.54
DGKA P23743 1/20 0.53
PRKCA P17252 1/20 0.53
PRKCE Q02156 1/20 0.53
PRKCQ Q04759 1/20 0.53
PRKCD Q05655 1/20 0.53
PRSS1 P07477 1/20 0.51
PRSS2 P07478 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL161065 1.00 TSHR (0.96) TSHRCYP3A4ATMTDP1LMNA
SCHEMBL14778978 1.00 TSHR (0.96) TSHRCYP3A4ATMTDP1LMNA
SCHEMBL37169 1.00 TSHR (0.96) TSHRCYP3A4ATMTDP1LMNA
SCHEMBL14778030 1.00 TSHR (0.96) TSHRCYP3A4ATMTDP1LMNA
SCHEMBL14779242 1.00 TSHR (0.96) TSHRCYP3A4ATMTDP1LMNA
SCHEMBL3204676 1.00 TSHR (0.96) TSHRCYP3A4ATMTDP1LMNA
SCHEMBL2049701 1.00 TSHR (0.96) TSHRCYP3A4ATMTDP1LMNA
SCHEMBL10493410 1.00 TSHR (0.96) TSHRCYP3A4ATMTDP1LMNA
SCHEMBL14778393 1.00 TSHR (0.96) TSHRCYP3A4ATMTDP1LMNA
SCHEMBL14778320 1.00 TSHR (0.96) TSHRCYP3A4ATMTDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2212746-B1 METHOD OF MAKING A LITHOGRAPHIC PRINTING PLATE AGFA NV (BE) 2020-04-29 EP disclosed
EP-1788434-B2 Method of making a lithographic printing plate AGFA NV (BE) 2019-01-02 EP disclosed
EP-2775351-B1 Apparatus and method for processing a lithographic printing plate AGFA GRAPHICS NV (BE) 2017-02-22 EP disclosed
EP-2755088-B1 Method of making a lithographic printing plate AGFA GRAPHICS NV (BE) 2016-07-27 EP disclosed
US-9354520-B2 Method of making a lithographic printing plate AGFA GRAPHICS NV (BE) 2016-05-31 US disclosed
US-20150360459-A1 APPARATUS AND METHOD FOR PROCESSING A LITHOGRAPHIC PRINTING PLATE AGFA GRAPHICS NV (BE) 2015-12-17 US disclosed
US-20150355548-A1 METHOD OF MAKING A LITHOGRAPHIC PRINTING PLATE ECO3 BV (BE) 2015-12-10 US disclosed
EP-2753981-B1 METHOD OF MAKING A LITHOGRAPHIC PRINTING PLATE AGFA GRAPHICS NV (BE) 2015-10-14 EP disclosed
WO-2014135536-A1 APPARATUS AND METHOD FOR PROCESSING A LITHOGRAPHIC PRINTING PLATE AGFA GRAPHICS NV (BE) 2014-09-12 WO disclosed
EP-2775351-A1 Apparatus and method for processing a lithographic printing plate AGFA GRAPHICS NV (BE) 2014-09-10 EP disclosed
EP-1342568-B1 Method of developing a heat-sensitive lithographic printing plate precursor with a gum solution AGFA GEVAERT NV (BE) 2005-10-12 EP disclosed
EP-1584470-A2 Method of developing a heat-sensitive lithographic printing plate precursor with a gum solution Agfa-Gevaert (BE) 2005-10-12 EP disclosed
US-20050089802-A1 Hydrophilic layer coated with hydrophobic thermoplastic polymer particles; exposed to infrared light to form precursor; mounted on print cylinder of printing press, develope precursor with aqueous liquid or ink AGFA-GEVAERT (BE) 2005-04-28 US disclosed
US-20050084797-A1 Contrast layer comprises a colorant capable of providing a visible image after exposure and development, and the image recording layer is free of the colorant; improved image-contrast and reduced staining AGFA-GEVAERT (BE) 2005-04-21 US disclosed
EP-1524113-A2 Method of making a heat-sensitive lithographic printing plate. Agfa-Gevaert (BE) 2005-04-20 EP disclosed
EP-1524112-A2 Heat-sensitive lithographic printing plate precursor Agfa-Gevaert (BE) 2005-04-20 EP disclosed
US-20030170570-A1 Inducing coalescence of the thermoplastic polymer particles at exposed areas of the coating; developing the precursor by applying a gum solution to the coating to remove non-exposed areas of the coating from the support AGFA-GEVAERT (BE) 2003-09-11 US disclosed
EP-1342568-A1 Method of developing a heat-sensitive lithographic printing plate precursor with a gum solution AGFA-GEVAERT N.V. (BE) 2003-09-10 EP disclosed
EP-0638436-A1 Surface protective agent and cleaning agent for lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1995-02-15 EP disclosed
WO-1980002429-A1 IMPROVED HOT MELT ADHESIVE COMPOSITION DU PONT (US) 1980-11-13 WO disclosed