Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | ITGAV | P06756 | 16/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 13/20 | 0.43 |
| ▸ | ITGB6 | P18564 | 7/20 | 0.42 |
| ▸ | ITGB8 | P26012 | 6/20 | 0.42 |
| ▸ | ITGB5 | P18084 | 5/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12705223 | 0.87 | CXCR4 (0.44) | APPITGAVITGB3ITGB6ITGB8 | |
| SCHEMBL12710167 | 0.81 | APP (0.43) | APPITGAVITGB3ITGB6ITGB8 | |
| SCHEMBL12705294 | 0.80 | APP (0.60) | APPITGAVITGB3ITGB6ITGB8 | |
| SCHEMBL12705474 | 0.79 | ITGAV (0.35) | ITGAVITGB3ITGB6ITGB8ITGB5 | |
| SCHEMBL12705298 | 0.76 | APP (0.48) | APPITGAVITGB3ITGB6ITGB8 | |
| SCHEMBL22223399 | 0.69 | ITGAV (0.58) | ITGAVITGB3ITGB6ITGB8ITGB5 | |
| SCHEMBL22497890 | 0.68 | ITGAV (0.55) | ITGAVITGB3ITGB6ITGB8ITGB5 | |
| SCHEMBL21339925 | 0.67 | CXCR4 (0.51) | ITGAVITGB3ITGB6ITGB8ITGB5 | |
| SCHEMBL14195956 | 0.67 | ITGAV (0.52) | ITGAVITGB3ITGB6ITGB8ITGB5 | |
| SCHEMBL13355375 | 0.67 | ITGAV (0.57) | ITGAVITGB3ITGB6ITGB8ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488513-B1 | 2,6-Diaminopyridine compounds for treating diseases associated with amyloid proteins or for treating ocular diseases | AC IMMUNE SA (CH) | 2017-12-27 | — | — | EP | disclosed |