Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1967676 | 0.91 | CHRM2 (0.45) | CHRM2CHRM1CHRM3HSD17B10CYP1A2 | |
| SCHEMBL584834 | 0.91 | CHRM2 (0.45) | CHRM2CHRM1CHRM3HSD17B10CYP1A2 | |
| SCHEMBL585389 | 0.91 | CHRM2 (0.45) | CHRM2CHRM1CHRM3HSD17B10CYP1A2 | |
| SCHEMBL18313954 | 0.91 | CHRM2 (0.45) | CHRM2CHRM1CHRM3HSD17B10CYP1A2 | |
| SCHEMBL1975610 | 0.91 | CHRM2 (0.45) | CHRM2CHRM1CHRM3HSD17B10CYP1A2 | |
| SCHEMBL15151157 | 0.91 | CHRM2 (0.45) | CHRM2CHRM1CHRM3HSD17B10CYP1A2 | |
| SCHEMBL7722108 | 0.91 | CHRM2 (0.45) | CHRM2CHRM1CHRM3HSD17B10CYP1A2 | |
| SCHEMBL23525346 | 0.88 | HSD17B10 (0.50) | CHRM2CHRM1CHRM3HSD17B10CYP1A2 | |
| SCHEMBL12121160 | 0.88 | HSD17B10 (0.50) | CHRM2CHRM1CHRM3HSD17B10CYP1A2 | |
| SCHEMBL1994228 | 0.88 | HSD17B10 (0.50) | CHRM2CHRM1CHRM3HSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110144085-A1 | TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2011-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144085-A1 | TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS | PIM1, PIM2, PIM3 | CHRM2 573/4885CHRM1 445/4885CHRM3 1024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.