SCHEMBL19756820

SCHEMBL19756820

O=C(O)CCCNC(=O)N[C@@H](CCCCNCc1ccc([123I])cc1)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 20/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14330722 0.92 FOLH1 (0.66) FOLH1
Iofolastat I 123 SCHEMBL12925130 0.90 FOLH1 (0.80) FOLH1
SCHEMBL17190075 0.82 FOLH1 (0.60) FOLH1
Mip-1095 I-123 SCHEMBL12925108 0.80 FOLH1 (0.80) FOLH1
SCHEMBL11977600 0.79 FOLH1 (1.00) FOLH1
SCHEMBL11977622 0.79 FOLH1 (1.00) FOLH1
SCHEMBL20312207 0.79 FOLH1 (1.00) FOLH1
SCHEMBL4673746 0.79 FOLH1 (1.00) FOLH1
SCHEMBL4336024 0.79 FOLH1 (1.00) FOLH1
SCHEMBL24336825 0.78 FOLH1 (1.00) FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170369454-A1 18F-LABELED TRIAZOLE CONTAINING PSMA INHIBITORS UNIV CORNELL (US) 2017-12-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170369454-A1 18F-LABELED TRIAZOLE CONTAINING PSMA INHIBITORS PSMA3, FOLH1, PSMA1 FOLH1 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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