SCHEMBL19759477

SCHEMBL19759477

C=CCCCCSC(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.37
ALDH1A1 P00352 1/20 0.35
ABCC4 O15439 1/20 0.32
MAPT P10636 1/20 0.32
TRPA1 O75762 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9308184 0.72
SCHEMBL1017559 0.71
SCHEMBL5692185 0.71 TSHR (0.46) TSHRALDH1A1ABCC4MAPTTRPA1
SCHEMBL1240083 0.71 TSHR (0.46) TSHRALDH1A1ABCC4MAPTTRPA1
SCHEMBL20603764 0.70
SCHEMBL20603580 0.70
SCHEMBL20603752 0.70
SCHEMBL20603729 0.70
SCHEMBL52388 0.69
SCHEMBL31576596 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3243224-B1 ELECTRONIC COMPONENT MERCK PATENT GMBH (DE) 2023-06-07 EP disclosed
US-10741778-B2 Electronic component including molecular layer MERCK PATENT GMBH (DE) 2020-08-11 US disclosed
US-20180006253-A1 ELECTRONIC COMPONENT MERCK PATENT GMBH (DE) 2018-01-04 US disclosed