Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | POLQ | O75417 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | WNT1 | P04628 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19244949 | 0.85 | NOTUM (0.46) | TRPV1NOTUMKDM4EKMT2AMLYCD | |
| SCHEMBL21987107 | 0.84 | TRPV1 (0.44) | TRPV1NOTUMKDM4EKMT2AMLYCD | |
| SCHEMBL19245037 | 0.84 | TRPV1 (0.44) | TRPV1NOTUMKDM4EKMT2AMLYCD | |
| SCHEMBL19211930 | 0.84 | TRPV1 (0.44) | TRPV1NOTUMKDM4EKMT2AMLYCD | |
| SCHEMBL19244948 | 0.84 | TRPV1 (0.44) | TRPV1NOTUMKDM4EKMT2AMLYCD | |
| SCHEMBL20733023 | 0.83 | TRPV1 (0.44) | TRPV1NOTUMKDM4EKMT2AMLYCD | |
| SCHEMBL20718652 | 0.83 | TRPV1 (0.46) | TRPV1NOTUMKDM4EKMT2AMLYCD | |
| SCHEMBL21065802 | 0.82 | TRPV1 (0.43) | TRPV1NOTUMKDM4EKMT2AMLYCD | |
| SCHEMBL19244950 | 0.82 | NOTUM (0.44) | TRPV1NOTUMKDM4EKMT2AHSD17B10 | |
| SCHEMBL19541136 | 0.82 | TRPV1 (0.48) | TRPV1NOTUMKDM4EKMT2AMLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190307126-A1 | SUBSTITUTED 2-THIOIMIDAZOLYLCARBOXAMIDES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-10-10 | — | — | US | disclosed |
| US-10368545-B2 | Substituted 2-thioimidazolylcarboxamides as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-08-06 | — | — | US | disclosed |
| US-20180007900-A1 | SUBSTITUTED 2-THIOIMIDAZOLYLCARBOXAMIDES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190307126-A1 | SUBSTITUTED 2-THIOIMIDAZOLYLCARBOXAMIDES AS PESTICIDES | TSNAX, DDT, PTMS | TRPV1 2157/4885NOTUM 315/4885KDM4E 642/4885 |
| US-10368545-B2 | Substituted 2-thioimidazolylcarboxamides as pesticides | TSNAX, DDT, PTMS | TRPV1 2157/4885NOTUM 315/4885KDM4E 642/4885 |
| US-20180007900-A1 | SUBSTITUTED 2-THIOIMIDAZOLYLCARBOXAMIDES AS PESTICIDES | TSNAX, DDT, PTMS | TRPV1 2157/4885NOTUM 315/4885KDM4E 642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.