SCHEMBL1976536

SCHEMBL1976536

Cc1nc(C)nc(C(Cl)(Cl)Cl)n1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.33
LMNA P02545 1/20 0.32
PKM P14618 1/20 0.32
CCNB2 O95067 1/20 0.31
CCNE2 O96020 1/20 0.31
CDK1 P06493 1/20 0.31
CDK4 P11802 1/20 0.31
CCNB1 P14635 1/20 0.31
CCNA2 P20248 1/20 0.31
CCND1 P24385 1/20 0.31
CCNE1 P24864 1/20 0.31
CDK2 P24941 1/20 0.31
CCNA1 P78396 1/20 0.31
CCNB3 Q8WWL7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9078603 0.84 CCNB2 (0.31) KDM4ECCNB2CCNE2CDK1CDK4
SCHEMBL9080867 0.82
SCHEMBL19750553 0.82
SCHEMBL11785129 0.82 KDM4E (0.33) KDM4ECCNB2CCNE2CDK1CDK4
SCHEMBL6294613 0.82 KDM4E (0.32) KDM4ELMNAPKM
SCHEMBL821298 0.78 GAA (0.37) KDM4ELMNAPKM
SCHEMBL15492875 0.78 KDM4E (0.30) KDM4ELMNAPKM
SCHEMBL10712195 0.78 HSD17B10 (0.36)
SCHEMBL9080796 0.78 KDM4E (0.33) KDM4ELMNAPKM
SCHEMBL9080889 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11697744-B2 High impact strength 3D printing materials derived from polycycloolefin monomers and crosslinkers PROMERUS, LLC (US) 2023-07-11 US disclosed
US-9588426-B2 Negative photoresist and methods of preparing and using the same BOE TECHNOLOGY GROUP CO., LTD. (CN) 2017-03-07 US disclosed
US-20140283702-A1 LITHOGRAPHIC PRINTING PLATE SUPPORT AND NEGATIVE PHOTOSENSITIVE LITHOGRAPHIC PRINTING PLATE MITSUBISHI PAPER MILLS LIMITED (JP) 2014-09-25 US disclosed
EP-2327700-A1 Dialkyl triazinamines and use thereof for combating undesired plant growth Bayer CropScience AG (DE) 2011-06-01 EP disclosed
WO-1999015511-A1 SUBSTITUTED TRIAZINES, METHOD FOR PRODUCING SAID SUBSTITUTED TRIAZINES, AND USE OF THE SAME AS PESTICIDES AND FUNGICIDES HOECHST SCHERING AGREVO GMBH (DE) 1999-04-01 WO disclosed
US-5489499-A DISCOLORATION INHIBITION, STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1996-02-06 US disclosed