⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1736515 | 0.56 | — | — | |
| SCHEMBL15248832 | 0.43 | GRIN2D (0.39) | — | |
| SCHEMBL6663337 | 0.43 | GRIN2D (0.39) | — | |
| Tert-Butanol SCHEMBL13915627 | 0.39 | — | — | |
| SCHEMBL1482218 | 0.39 | — | — | |
| SCHEMBL1494262 | 0.37 | — | — | |
| SCHEMBL1913 | 0.35 | — | — | |
| SCHEMBL3426362 | 0.35 | — | — | |
| SCHEMBL2151842 | 0.35 | TSHR (0.43) | — | |
| SCHEMBL8358538 | 0.35 | TSHR (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2665722-B1 | PROCESS FOR THE PREPARATION OF DIOL SULFONES | DSM SINOCHEM PHARM NL BV (NL) | 2016-08-17 | — | — | EP | claimed |
| EP-2334640-B1 | METHODS FOR PRODUCING PARICALCITOL | AZAD PHARMACEUTICAL INGREDIENTS AG (CH) | 2015-12-23 | — | — | EP | claimed |
| US-9212136-B2 | Methods for producing paricalcitol | AZAD PHARMACEUTICALS INGREDIENTS AG (CH) | 2015-12-15 | — | — | US | claimed |
| EP-2665723-B1 | PROCESS FOR THE PREPARATION OF STATINS IN THE PRESENCE OF BASE | DSM SINOCHEM PHARM NL BV (NL) | 2015-07-22 | — | — | EP | claimed |
| EP-2513046-B1 | PROCESS FOR THE PREPARATION OF 4-BROMOMETHYL-[1,1'-BIPHENYL]-2'-CARBONITRILE | SANOFI SA (FR) | 2015-07-08 | — | — | EP | claimed |
| US-20110184199-A1 | Methods For Producing Paricalcitol | AZAD PHARMA AG (CH) | 2011-07-28 | — | — | US | claimed |
| EP-2334640-A2 | METHODS FOR PRODUCING PARICALCITOL | Azad Pharmaceutical Ingredients AG (CH) | 2011-06-22 | — | — | EP | claimed |
| WO-2010009879-A2 | METHODS FOR PRODUCING PARICALCITOL | AZAD PHARMACEUTICAL INGREDIENTS AG (CH) | 2010-01-28 | — | — | WO | claimed |
| US-5543528-A | Imidazolines | SANOFI (FR) | 1996-08-06 | — | — | US | claimed |
| EP-0500409-B1 | 4-Pyrimidinone derivatives, their preparation and their application in therapy | SYNTHELABO (FR) | 1996-03-20 | — | — | EP | claimed |
| US-5434167-A | Angiotensin II antagonists | SANOFI (FR) | 1995-07-18 | — | — | US | claimed |
| CN-118063392-A | Improved process for preparing statin precursors | 灿盛制药有限公司荷兰公司 | 2024-05-24 | — | — | CN | disclosed |
| EP-2334640-B1 | METHODS FOR PRODUCING PARICALCITOL | AZAD PHARMACEUTICAL INGREDIENTS AG (CH) | 2015-12-23 | — | — | EP | disclosed |
| US-9212136-B2 | Methods for producing paricalcitol | AZAD PHARMACEUTICALS INGREDIENTS AG (CH) | 2015-12-15 | — | — | US | disclosed |
| US-8551999-B2 | Heterocyclic compound and pharmaceutical composition thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-10-08 | — | — | US | disclosed |
| EP-0562936-A1 | Imidazolines N-substituted by a biphenylmethyl group, their preparation, the pharmaceutical compositions containing them | SANOFI (FR) | 1993-09-29 | — | — | EP | disclosed |
| CN-1072682-A | SUBSTITUTED PYRIMIDINES | AMERICAN HOME PROD (US) | 1993-06-02 | — | — | CN | disclosed |
| US-5137889-A | Hypotensive agents; coronary vasodilators; calcium antagonists; antiinflammatory agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| US-5034395-A | Hypotensive agents, carboxylated dihydropyridines | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0145434-A2 | Novel dihydropyridine derivatives and process for preparing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-06-19 | — | — | EP | disclosed |