⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1247084 | 0.75 | — | — | |
| SCHEMBL1246937 | 0.71 | — | — | |
| SCHEMBL3564249 | 0.69 | — | — | |
| SCHEMBL3560334 | 0.67 | — | — | |
| SCHEMBL3557159 | 0.67 | — | — | |
| SCHEMBL3710180 | 0.67 | — | — | |
| SCHEMBL27267 | 0.65 | — | — | |
| SCHEMBL4222234 | 0.63 | — | — | |
| Alcohol SCHEMBL29169498 | 0.62 | — | — | |
| SCHEMBL28187686 | 0.62 | CHRM2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 678 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11708344-B2 | Flavone derivatives for the treatment and prophylaxis of hepatitis B virus disease | HOFFMANN-LA ROCHE INC. (US) | 2023-07-25 | — | — | US | claimed |
| CN-116003328-A | Diaryl hydantoin compounds | 加利福尼亚大学董事会 | 2023-04-25 | — | — | CN | claimed |
| CN-115504973-A | Benzisoxazole compound, preparation method thereof, pharmaceutical composition and application | 中国医学科学院药物研究所 | 2022-12-23 | — | — | CN | claimed |
| CN-115466251-A | Fused heterocyclic compound, preparation method thereof, pharmaceutical composition and application | 中国医学科学院药物研究所 | 2022-12-13 | — | — | CN | claimed |
| US-20220388969-A1 | SUBSTITUTED 3,4-DIHYDROQUINAZOLINE FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN-LA ROCHE INC. (US) | 2022-12-08 | — | — | US | claimed |
| EP-4021895-A1 | NOVEL QUINAZOLINE COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS DISEASE | F. Hoffmann-La Roche AG (CH) | 2022-07-06 | — | — | EP | claimed |
| CN-114591318-A | Pyrazolo heterocyclic compound, preparation method thereof, pharmaceutical composition and application | 中国医学科学院药物研究所 | 2022-06-07 | — | — | CN | claimed |
| CN-114507243-A | Isothiazole heterocyclic compound, preparation method thereof, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2022-05-17 | — | — | CN | claimed |
| CN-114507227-A | Benzisothiazole compound, preparation method thereof, pharmaceutical composition and application | 中国医学科学院药物研究所 | 2022-05-17 | — | — | CN | claimed |
| CN-114502538-A | Substituted 3, 4-dihydroquinazolines for the treatment and prevention of hepatitis B virus infection | 豪夫迈·罗氏有限公司 | 2022-05-13 | — | — | CN | claimed |
| EP-0693060-A1 | METHOD OF PREPARATION OF 6-FLUORO-2-HALOGEN QUINOLINE | Aventis Pharma S.A. (FR) | 1996-01-24 | — | — | EP | claimed |
| US-5484921-A | Process for preparing benzo[b]naphthyridines | LABORATOIRE ROGER BELLON (FR) | 1996-01-16 | — | — | US | claimed |
| EP-0641341-A1 | METHOD FOR PREPARING BENZO b]NAPHTHYRIDINES | LABORATOIRE ROGER BELLON (FR) | 1995-03-08 | — | — | EP | claimed |
| WO-1994024113-A1 | METHOD OF PREPARATION OF 6-FLUORO-2-HALOGEN QUINOLINE | RHONE-POULENC RORER S.A. (FR) | 1994-10-27 | — | — | WO | claimed |
| EP-0607329-A1 | NEW DERIVATIVES OF FLUORO-QUINOLINE CARBOXYLIC-3 ACID AND PREPARATION THEREOF | LABORATOIRE ROGER BELLON (FR) | 1994-07-27 | — | — | EP | claimed |
| EP-0538101-A1 | Process for the preparation of benzo(b)naphthyridines | LABORATOIRE ROGER BELLON (FR) | 1993-04-21 | — | — | EP | claimed |
| EP-0538100-A1 | New fluoro-quinolin-3-carboxylic acid derivatives and their preparation | LABORATOIRE ROGER BELLON (FR) | 1993-04-21 | — | — | EP | claimed |
| WO-1993007127-A1 | NEW DERIVATIVES OF FLUORO-QUINOLINE CARBOXYLIC-3 ACID AND PREPARATION THEREOF | LABORATOIRE ROGER BELLON (FR) | 1993-04-15 | — | — | WO | claimed |
| WO-1993007145-A1 | METHOD FOR PREPARING BENZO[b]NAPHTHYRIDINES | LABORATOIRE ROGER BELLON (FR) | 1993-04-15 | — | — | WO | claimed |
| US-4552951-A | Disperse and acid azo dyes having one or two cinnamoyl substituents on a phenyl diazonium moiety and containing an aniline, tetrahydroquinoline or benzomorpholine coupler | EASTMAN KODAK COMPANY (US) | 1985-11-12 | — | — | US | claimed |