Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1358014 | 0.93 | CYP3A4 (0.37) | CYP3A4 | |
| SCHEMBL1359501 | 0.93 | CYP3A4 (0.37) | CYP3A4 | |
| SCHEMBL1360031 | 0.88 | CYP3A4 (0.37) | CYP3A4 | |
| SCHEMBL3144591 | 0.88 | CYP3A4 (0.37) | CYP3A4 | |
| SCHEMBL1358412 | 0.88 | CYP3A4 (0.37) | CYP3A4 | |
| SCHEMBL1359539 | 0.88 | CYP3A4 (0.32) | CYP3A4 | |
| SCHEMBL1359467 | 0.86 | CYP3A4 (0.39) | CYP3A4 | |
| SCHEMBL1357838 | 0.85 | CYP3A4 (0.32) | CYP3A4 | |
| SCHEMBL1359544 | 0.83 | CYP3A4 (0.34) | CYP3A4 | |
| SCHEMBL1359043 | 0.81 | CCNT1 (0.33) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334662-A1 | PYRINE OR PYRAZINE DERIVATIVES FOR TREATING HCV | F. Hoffmann-La Roche AG (CH) | 2011-06-22 | — | — | EP | claimed |