Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K12 | Q12852 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16220305 | 0.84 | MAP3K12 (0.59) | MAP3K12 | |
| SCHEMBL16220163 | 0.81 | MAP3K12 (0.76) | MAP3K12 | |
| SCHEMBL16220389 | 0.80 | MAP3K12 (0.74) | MAP3K12 | |
| SCHEMBL16220303 | 0.77 | MAP3K12 (0.62) | MAP3K12 | |
| SCHEMBL16220402 | 0.75 | MAP3K12 (0.58) | MAP3K12 | |
| SCHEMBL16220424 | 0.74 | MAP3K12 (0.69) | MAP3K12 | |
| SCHEMBL16220414 | 0.73 | MAP3K12 (0.72) | MAP3K12 | |
| SCHEMBL16220413 | 0.72 | MAP3K12 (0.68) | MAP3K12 | |
| SCHEMBL17507023 | 0.71 | MAP3K12 (0.55) | MAP3K12 | |
| SCHEMBL17507076 | 0.69 | MAP3K12 (0.56) | MAP3K12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9868720-B2 | C-linked heterocycloaklyl substituted pyrimidines and their uses | GENENTECH, INC. (US) | 2018-01-16 | — | — | US | disclosed |