Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | S100A4 | P26447 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18079825 | 0.77 | ADORA2A (0.42) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL16544651 | 0.76 | PDK2 (0.41) | PDK2KDM4ELMNAMAPTCYP2D6 | |
| SCHEMBL16810667 | 0.76 | PDK2 (0.54) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL20415443 | 0.75 | PDK2 (0.40) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL18079822 | 0.75 | PDK2 (0.43) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL18160253 | 0.74 | PDK2 (0.49) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL16544649 | 0.74 | PDK2 (0.42) | PDK2KDM4ELMNAMAPTCYP2D6 | |
| SCHEMBL10053123 | 0.73 | PDK2 (0.56) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL16810678 | 0.73 | PDK2 (0.56) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL29484645 | 0.73 | PDK2 (0.56) | PDK2KDM4EMEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3080229-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-01-17 | — | — | EP | disclosed |