Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 20/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3605637 | 0.91 | GCK (0.68) | GCKKCNH2 | |
| SCHEMBL12021699 | 0.89 | GCK (0.61) | GCKKCNH2 | |
| SCHEMBL12021712 | 0.89 | GCK (0.65) | GCKKCNH2 | |
| SCHEMBL12021707 | 0.88 | GCK (0.64) | GCKKCNH2 | |
| SCHEMBL12021654 | 0.83 | GCK (0.67) | GCKKCNH2 | |
| SCHEMBL1147249 | 0.82 | GCK (0.74) | GCKKCNH2 | |
| SCHEMBL13891541 | 0.82 | GCK (0.74) | GCKKCNH2 | |
| SCHEMBL2667446 | 0.81 | GCK (0.62) | GCKKCNH2 | |
| SCHEMBL4581136 | 0.81 | GCK (0.61) | GCKKCNH2 | |
| SCHEMBL1107459 | 0.81 | GCK (0.74) | GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1600442-B1 | HETEROARYLCARBAMOYLBENZENE DERIVATIVE | MSD KK (JP) | 2018-01-17 | — | — | EP | disclosed |