Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 15/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19780049 | 0.84 | NPC1 (0.67) | KLKB1TSHRNPC1LMNAALDH1A1 | |
| SCHEMBL20531612 | 0.76 | KLKB1 (0.63) | KLKB1TSHR | |
| SCHEMBL20531601 | 0.74 | KLKB1 (0.62) | KLKB1TSHR | |
| SCHEMBL19780055 | 0.74 | KMT2A (0.54) | KLKB1NPC1LMNAALDH1A1KMT2A | |
| SCHEMBL19780369 | 0.74 | KLKB1 (0.61) | KLKB1NPC1LMNAALDH1A1KMT2A | |
| SCHEMBL19780317 | 0.70 | KLKB1 (0.49) | KLKB1 | |
| SCHEMBL20531458 | 0.70 | PTGER4 (0.48) | KLKB1 | |
| SCHEMBL21028252 | 0.70 | KLKB1 (0.44) | KLKB1 | |
| SCHEMBL20531434 | 0.69 | KLKB1 (0.50) | KLKB1TSHR | |
| SCHEMBL19779784 | 0.69 | KLKB1 (0.50) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018011628-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2018-01-18 | — | — | WO | disclosed |