Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 15/20 | 0.59 |
| ▸ | MAP4K1 | Q92918 | 7/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20531585 | 0.84 | KLKB1 (0.62) | KLKB1MAP4K1MAPK1POLB | |
| SCHEMBL19780070 | 0.84 | KLKB1 (0.60) | KLKB1MAP4K1MAPK1 | |
| SCHEMBL22276469 | 0.76 | KLKB1 (0.48) | KLKB1MAP4K1 | |
| SCHEMBL19779879 | 0.76 | KLKB1 (0.52) | KLKB1MAP4K1 | |
| SCHEMBL19779880 | 0.75 | KLKB1 (0.50) | KLKB1MAP4K1 | |
| SCHEMBL19779816 | 0.74 | KLKB1 (0.80) | KLKB1MAP4K1MAPK1POLB | |
| SCHEMBL19780359 | 0.74 | KLKB1 (1.00) | KLKB1MAP4K1 | |
| SCHEMBL19780598 | 0.74 | KLKB1 (1.00) | KLKB1MAP4K1 | |
| SCHEMBL19780379 | 0.73 | KLKB1 (1.00) | KLKB1MAP4K1MAPK1 | |
| SCHEMBL19779817 | 0.73 | KLKB1 (0.59) | KLKB1MAP4K1MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018011628-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2018-01-18 | — | — | WO | disclosed |