SCHEMBL1978076

SCHEMBL1978076

CCCCCCCCCCCCCCCCCCCCCCCC[C@@H](C(=O)OC)[C@@H](CCCCCCCCCCCCCC=C[C@@H]1C[C@@H]1CCCCCCCCCCCCCCCCCC[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](C)CCCCCCCCCCCCCCCCCC)OC(C)=O

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 3/20 0.35
PDE4D Q08499 4/20 0.34
ALOX5 P09917 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15135038 1.00 TRPV1 (0.35) TRPV1PDE4DALOX5
SCHEMBL15135036 1.00 TRPV1 (0.35) TRPV1PDE4DALOX5
SCHEMBL1114618 0.89 TRPV1 (0.37) TRPV1ALOX5
SCHEMBL15664548 0.80 EPHX2 (0.31)
SCHEMBL15664547 0.80 EPHX2 (0.31)
SCHEMBL1975014 0.79 LPAR1 (0.33)
SCHEMBL1975012 0.79 LPAR1 (0.33)
SCHEMBL1114915 0.76
SCHEMBL15667724 0.76 ZDHHC7 (0.30)
SCHEMBL15679449 0.76 ZDHHC7 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8728515-B2 Adjuvants for use in vaccination BANGOR UNIVERSITY (GB) 2014-05-20 US disclosed
EP-2620158-A1 Adjuvants for use in vaccination Bangor University (GB) 2013-07-31 EP disclosed
US-20110142916-A1 Adjuvants for Use in Vaccination BANGOR UNIVERSITY (GB) 2011-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110142916-A1 Adjuvants for Use in Vaccination NR1H3, NR1H2, INTS6 TRPV1 3262/4885PDE4D 4538/4885ALOX5 663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.