Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | MGAM | O43451 | 2/20 | 0.34 |
| ▸ | SI | P14410 | 2/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19780901 | 0.84 | TSHR (0.37) | TSHRHSD17B10TET2RECQLGAA | |
| SCHEMBL20362833 | 0.81 | TSHR (0.41) | TSHRHSD17B10TET2RECQLGAA | |
| SCHEMBL3604649 | 0.76 | CA12 (0.44) | TSHRHSD17B10TET2RECQLGAA | |
| SCHEMBL21946049 | 0.74 | TSHR (0.40) | TSHRHSD17B10TET2RECQLGAA | |
| Hydrochloric Acid SCHEMBL18577216 | 0.74 | CA12 (0.43) | TSHRHSD17B10TET2RECQLGAA | |
| SCHEMBL16894217 | 0.74 | TSHR (0.40) | TSHRHSD17B10TET2RECQLGAA | |
| SCHEMBL73416 | 0.74 | TSHR (0.56) | TSHRHSD17B10TET2RECQLGAA | |
| SCHEMBL3076938 | 0.73 | TET2 (0.36) | TSHRHSD17B10TET2RECQLGAA | |
| SCHEMBL21708634 | 0.72 | TET2 (0.39) | TSHRHSD17B10TET2RECQLGAA | |
| SCHEMBL11237051 | 0.72 | TET2 (0.39) | TSHRHSD17B10TET2RECQLGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018011320-A1 | PNA PROBE | Destina Genomica S.L. (ES) | 2018-01-18 | — | — | WO | disclosed |