SCHEMBL19782439

SCHEMBL19782439

COC(=O)c1cc(NC(=O)OCCOc2cc3sc(-c4cc(C)cc5nc(OC)cnc45)nc3cc2F)ccn1

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 20/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23463060 0.94 F2RL3 (0.62) F2RL3
SCHEMBL23463068 0.94 F2RL3 (0.61) F2RL3
SCHEMBL23462917 0.93 F2RL3 (0.60) F2RL3
SCHEMBL23462931 0.93 F2RL3 (0.64) F2RL3
SCHEMBL21395545 0.91 F2RL3 (0.71) F2RL3
SCHEMBL21395684 0.90 F2RL3 (0.61) F2RL3
SCHEMBL21395657 0.90 F2RL3 (0.62) F2RL3
SCHEMBL21395750 0.90 F2RL3 (0.69) F2RL3
SCHEMBL21395702 0.89 F2RL3 (0.73) F2RL3
SCHEMBL21424435 0.89 F2RL3 (0.71) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018013774-A1 BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2018-01-18 WO disclosed