SCHEMBL19782467

SCHEMBL19782467

COc1cnc2c(-c3nc4c(C)cc(OC(C)CO)nc4s3)cc(C)cc2n1

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 19/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19782468 0.88 F2RL3 (0.53) F2RL3
SCHEMBL30187549 0.86 F2RL3 (0.56) F2RL3
SCHEMBL19783230 0.86 F2RL3 (0.56) F2RL3
SCHEMBL30189806 0.85 F2RL3 (0.50) F2RL3
SCHEMBL21379695 0.85 F2RL3 (0.50) F2RL3
SCHEMBL19783234 0.85 F2RL3 (0.50) F2RL3
SCHEMBL30189841 0.85 F2RL3 (0.51) F2RL3
SCHEMBL19783235 0.85 F2RL3 (0.51) F2RL3
SCHEMBL22341907 0.82 F2RL3 (0.50) F2RL3
SCHEMBL19782469 0.82 F2RL3 (0.46) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018013774-A1 BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2018-01-18 WO disclosed