SCHEMBL19782576

SCHEMBL19782576

CCc1cc2c(cc1C)CC(c1cc(C)cc3nc(OC)cnc13)=C2

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ F2RL3 Q96RI0 20/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19783305 0.76 F2RL3 (0.42) F2RL3
SCHEMBL19783346 0.73 F2RL3 (0.42) F2RL3
SCHEMBL19783469 0.69 HTT (0.43) F2RL3
SCHEMBL19776972 0.68 F2RL3 (0.46) F2RL3
SCHEMBL19775930 0.66 F2RL3 (0.37) F2RL3
SCHEMBL19776969 0.65 F2RL3 (0.44) F2RL3
SCHEMBL19783100 0.65 F2RL3 (0.53) F2RL3
SCHEMBL19776649 0.64 F2RL3 (0.51) F2RL3
SCHEMBL21922680 0.63 F2RL3 (0.51) F2RL3
SCHEMBL29783692 0.63 F2RL3 (0.65) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018013774-A1 BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2018-01-18 — — WO disclosed
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