Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 20/20 | 0.79 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.79 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13833390 | 0.88 | HDAC2 (1.00) | HDAC2HDAC1HDAC3 | |
| SCHEMBL13833469 | 0.87 | HDAC2 (0.74) | HDAC2HDAC1HDAC3 | |
| SCHEMBL19204267 | 0.85 | HDAC2 (0.79) | HDAC2HDAC1HDAC3 | |
| SCHEMBL13833464 | 0.85 | HDAC2 (1.00) | HDAC2HDAC1HDAC3 | |
| SCHEMBL18273871 | 0.82 | HDAC2 (0.77) | HDAC2HDAC1HDAC3 | |
| SCHEMBL18375004 | 0.81 | HDAC2 (1.00) | HDAC2HDAC1HDAC3 | |
| SCHEMBL13833351 | 0.80 | HDAC2 (0.71) | HDAC2HDAC1HDAC3 | |
| SCHEMBL18273910 | 0.80 | HDAC2 (0.80) | HDAC2HDAC1HDAC3 | |
| SCHEMBL19204395 | 0.79 | HDAC2 (0.77) | HDAC2HDAC1HDAC3 | |
| SCHEMBL18375012 | 0.78 | HDAC2 (1.00) | HDAC2HDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11572368-B2 | Inhibitors of histone deacetylase | THE GENERAL HOSPITAL CORPORATION (US) | 2023-02-07 | — | — | US | disclosed |
| US-20180016282-A9 | INHIBITORS OF HISTONE DEACETYLASE | HOWARD HUGHES MEDICAL INSTITUTE | 2018-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11572368-B2 | Inhibitors of histone deacetylase | HDAC2, HDAC1, HDAC11 | HDAC2 1/4885HDAC1 2/4885HDAC3 7/4885 |
| US-20180016282-A9 | INHIBITORS OF HISTONE DEACETYLASE | HDAC2, HDAC1, HDAC11 | HDAC2 1/4885HDAC1 2/4885HDAC3 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.