SCHEMBL19782733

SCHEMBL19782733

Cc1cn2c(n1)OCCC2

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24879804 0.88
SCHEMBL19888411 0.78 KMT2A (0.33) KMT2A
SCHEMBL19888410 0.77 KMT2A (0.33) KMT2A
SCHEMBL21395389 0.77 KMT2A (0.30) KMT2A
SCHEMBL21395321 0.77 PIK3CD (0.31) KMT2A
SCHEMBL3469461 0.70 CHRM1 (0.39) KMT2A
SCHEMBL7916624 0.65
SCHEMBL22166762 0.65
SCHEMBL14576846 0.65 CCR1 (0.48) KMT2A
SCHEMBL24880230 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3555070-B1 AMINE-SUBSTITUTED HETEROCYCLIC COMPOUNDS AS EHMT2 INHIBITORS AND METHODS OF USE THEREOF EPIZYME INC (US) 2023-08-09 EP disclosed
WO-2018033455-A1 CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-02-22 WO disclosed
WO-2018013774-A1 BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2018-01-18 WO disclosed