SCHEMBL19782737

SCHEMBL19782737

COc1cnc2c(-c3nc4cc(F)c(OCCOC(=O)Nc5cnc(C)nc5)cc4s3)cc(C#N)cc2n1

nearest known ligand 0.73

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 20/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31113699 0.91 F2RL3 (0.73) F2RL3
SCHEMBL21396027 0.91 F2RL3 (0.73) F2RL3
SCHEMBL21396178 0.89 F2RL3 (0.70) F2RL3
SCHEMBL19782735 0.88 F2RL3 (0.70) F2RL3
SCHEMBL31113846 0.88 F2RL3 (0.70) F2RL3
SCHEMBL21396179 0.86 F2RL3 (0.71) F2RL3
SCHEMBL31113580 0.86 F2RL3 (0.71) F2RL3
SCHEMBL21395559 0.85 F2RL3 (0.67) F2RL3
SCHEMBL21941297 0.84 F2RL3 (1.00) F2RL3
SCHEMBL19784275 0.84 F2RL3 (1.00) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018013774-A1 BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2018-01-18 WO disclosed