SCHEMBL19782776

SCHEMBL19782776

COCC(C)Oc1cc2sc(-c3cc(Cl)cc4cc(OC)cnc34)nc2c(Cl)c1F

nearest known ligand 0.42

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 14/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19783209 0.91 F2RL3 (0.44) F2RL3
SCHEMBL21379403 0.87 F2RL3 (0.43) F2RL3
SCHEMBL21379653 0.87 F2RL3 (0.44) F2RL3
SCHEMBL19783208 0.87 F2RL3 (0.44) F2RL3
SCHEMBL30189873 0.87 F2RL3 (0.44) F2RL3
SCHEMBL19783516 0.86 F2RL3 (0.54) F2RL3
SCHEMBL21396092 0.84 F2RL3 (0.49) F2RL3
SCHEMBL21396170 0.84 F2RL3 (0.48) F2RL3
SCHEMBL21395866 0.84 F2RL3 (0.47) F2RL3
SCHEMBL21395641 0.83 F2RL3 (0.47) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018013774-A1 BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2018-01-18 WO disclosed