SCHEMBL19782829

SCHEMBL19782829

COc1cc(C)cc2sc(-c3cc(C)cc4nc(OC(F)F)cnc34)nc12

nearest known ligand 0.80

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 19/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21395655 0.93 F2RL3 (0.85) F2RL3
SCHEMBL19782831 0.89 F2RL3 (1.00) F2RL3
SCHEMBL21395485 0.87 F2RL3 (1.00) F2RL3
SCHEMBL21395542 0.86 F2RL3 (0.75) F2RL3
SCHEMBL19783242 0.85 F2RL3 (1.00) F2RL3
SCHEMBL30189892 0.84 F2RL3 (0.70) F2RL3
SCHEMBL19783066 0.84 F2RL3 (0.70) F2RL3
SCHEMBL21395493 0.83 F2RL3 (0.76) F2RL3
SCHEMBL21395369 0.82 F2RL3 (0.82) F2RL3
SCHEMBL21395420 0.82 F2RL3 (0.77) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018013774-A1 BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2018-01-18 WO disclosed