SCHEMBL19782875

SCHEMBL19782875

Cc1cc(Br)c2ncc(OS(=O)C(F)(F)F)nc2c1

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 13/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19782874 0.77 F2RL3 (0.37) F2RL3
SCHEMBL19776431 0.76 F2RL3 (0.44) F2RL3
SCHEMBL19783320 0.75 F2RL3 (0.41) F2RL3
SCHEMBL9089475 0.74 F2RL3 (0.60) F2RL3
SCHEMBL29481749 0.74 F2RL3 (0.60) F2RL3
SCHEMBL19783799 0.74 F2RL3 (0.39) F2RL3
SCHEMBL9090122 0.72 CCR1 (0.35) F2RL3
SCHEMBL19782608 0.71 F2RL3 (0.33) F2RL3
SCHEMBL19782791 0.71 MEN1 (0.50) F2RL3
SCHEMBL21379355 0.69 KDM4E (0.43) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018013774-A1 BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2018-01-18 WO disclosed