Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL12 | P48061 | 2/20 | 0.76 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | CDC7 | O00311 | 3/20 | 0.46 |
| ▸ | PIM1 | P11309 | 2/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22066250 | 0.94 | CXCL12 (0.80) | CXCL12PDGFRBKITKDRCDC7 | |
| SCHEMBL19782903 | 0.86 | CXCL12 (1.00) | CXCL12PDGFRBKITKDRCDC7 | |
| SCHEMBL29838763 | 0.86 | CXCL12 (1.00) | CXCL12PDGFRBKITKDRCDC7 | |
| SCHEMBL19782686 | 0.86 | CXCL12 (0.91) | CXCL12PDGFRBKITKDRCDC7 | |
| SCHEMBL19782928 | 0.82 | CXCL12 (0.68) | CXCL12PDGFRBKITKDRCDC7 | |
| SCHEMBL19783008 | 0.81 | CXCL12 (0.74) | CXCL12PDGFRBKITKDRCDC7 | |
| SCHEMBL19782360 | 0.81 | CXCL12 (0.74) | CXCL12PDGFRBKITKDRCDC7 | |
| SCHEMBL19783006 | 0.81 | CXCL12 (0.73) | CXCL12PDGFRBKITKDRCDC7 | |
| SCHEMBL19782836 | 0.81 | CXCL12 (0.69) | CXCL12PDGFRBKITKDRCDC7 | |
| SCHEMBL19782680 | 0.80 | CXCL12 (0.72) | CXCL12PDGFRBKITKDRCDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018011376-A1 | PYRIMIDINONE DERIVATIVES AND USES THEREOF TO NEUTRALIZE THE BIOLOGICAL ACTIVITY OF CHEMOKINES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS - (FR) | 2018-01-18 | — | — | WO | disclosed |