SCHEMBL19783028

SCHEMBL19783028

CCOc1cnc2c(-c3nc4cc(F)c(OC(C)COC(=O)Nc5cnc(CCOP(O)O)nc5)cc4s3)cc(C)cc2n1

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 20/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21395919 0.92 F2RL3 (0.63) F2RL3
SCHEMBL21395492 0.91 F2RL3 (0.58) F2RL3
SCHEMBL23462906 0.90 F2RL3 (0.68) F2RL3
SCHEMBL19783466 0.90 F2RL3 (0.68) F2RL3
SCHEMBL21395861 0.89 F2RL3 (0.66) F2RL3
SCHEMBL21395488 0.88 F2RL3 (0.72) F2RL3
SCHEMBL23462915 0.88 F2RL3 (0.64) F2RL3
SCHEMBL21395470 0.88 F2RL3 (0.52) F2RL3
SCHEMBL21395673 0.87 F2RL3 (0.68) F2RL3
SCHEMBL21395707 0.87 F2RL3 (0.67) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018013774-A1 BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2018-01-18 WO disclosed