SCHEMBL19783143

SCHEMBL19783143

COc1cnc2c(-c3nc4cc(F)c(OC(C)COC(=O)Cl)nc4s3)cc(C)cc2n1

nearest known ligand 0.47

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 20/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23463256 0.94 F2RL3 (0.44) F2RL3
SCHEMBL19782719 0.94 F2RL3 (0.44) F2RL3
SCHEMBL19783202 0.88 F2RL3 (0.48) F2RL3
SCHEMBL21379539 0.88 F2RL3 (0.48) F2RL3
SCHEMBL21395610 0.87 F2RL3 (0.59) F2RL3
SCHEMBL21379635 0.87 F2RL3 (0.48) F2RL3
SCHEMBL19783136 0.87 F2RL3 (0.48) F2RL3
SCHEMBL19782615 0.87 F2RL3 (0.49) F2RL3
SCHEMBL21396150 0.86 F2RL3 (0.53) F2RL3
SCHEMBL21395594 0.86 F2RL3 (0.55) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018013774-A1 BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2018-01-18 WO disclosed