Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 9/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.33 |
| ▸ | FEN1 | P39748 | 4/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19783061 | 0.86 | ACACB (0.36) | ACACB | |
| SCHEMBL19782765 | 0.84 | ALOX5AP (0.37) | ACACBALOX5APFEN1BRAF | |
| SCHEMBL19783177 | 0.83 | ACACB (0.39) | ACACB | |
| SCHEMBL19783176 | 0.83 | ACACB (0.39) | ACACB | |
| SCHEMBL21379681 | 0.83 | ACACB (0.33) | ACACB | |
| SCHEMBL19783231 | 0.83 | ACACB (0.33) | ACACB | |
| SCHEMBL30189752 | 0.83 | ACACB (0.33) | ACACB | |
| SCHEMBL21379514 | 0.79 | ACACB (0.39) | ACACBKMT2A | |
| SCHEMBL30189708 | 0.79 | ACACB (0.39) | ACACBKMT2A | |
| SCHEMBL21379513 | 0.79 | ACACB (0.39) | ACACBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013774-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-01-18 | — | — | WO | disclosed |