Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | F2RL3 | Q96RI0 | 4/20 | 0.36 |
| ▸ | ACACB | O00763 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21395346 | 0.86 | ACACB (0.36) | F2RL3ACACB | |
| SCHEMBL31114077 | 0.86 | ACACB (0.36) | F2RL3ACACB | |
| SCHEMBL31113883 | 0.85 | F2RL3 (0.35) | F2RL3ACACB | |
| SCHEMBL19783165 | 0.85 | F2RL3 (0.35) | F2RL3ACACB | |
| SCHEMBL19782470 | 0.85 | F2RL3 (0.37) | F2RL3MAPTMEN1LMNAKMT2A | |
| SCHEMBL19783176 | 0.81 | ACACB (0.39) | ACACB | |
| SCHEMBL19783177 | 0.81 | ACACB (0.39) | ACACB | |
| SCHEMBL21395610 | 0.80 | F2RL3 (0.59) | F2RL3 | |
| SCHEMBL21379457 | 0.77 | ACACB (0.35) | F2RL3ACACBMAPT | |
| SCHEMBL19782777 | 0.77 | ACACB (0.35) | F2RL3ACACBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013774-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-01-18 | — | — | WO | disclosed |