Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.53 |
| ▸ | CA1 | P00915 | 5/20 | 0.53 |
| ▸ | CA2 | P00918 | 5/20 | 0.53 |
| ▸ | CA9 | Q16790 | 5/20 | 0.53 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 5/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30189758 | 1.00 | CA12 (0.53) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL13306449 | 0.88 | CA12 (0.58) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL16406354 | 0.87 | CA12 (0.55) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL30189676 | 0.85 | CA12 (0.56) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL19783396 | 0.85 | CA12 (0.56) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL31113888 | 0.84 | CA12 (0.55) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL19783146 | 0.84 | CA12 (0.55) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL21460898 | 0.83 | CA12 (0.56) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL13306476 | 0.82 | CA12 (0.55) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL19783401 | 0.82 | CA12 (0.57) | CA12CA1CA2CA9PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |
| WO-2018013774-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-01-18 | — | — | WO | disclosed |