Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 12/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30187613 | 0.91 | F2RL3 (0.53) | F2RL3 | |
| SCHEMBL19783249 | 0.91 | F2RL3 (0.53) | F2RL3 | |
| SCHEMBL19783126 | 0.89 | F2RL3 (0.66) | F2RL3 | |
| SCHEMBL19783290 | 0.85 | F2RL3 (0.55) | F2RL3 | |
| SCHEMBL30189897 | 0.85 | F2RL3 (0.55) | F2RL3 | |
| SCHEMBL30189874 | 0.80 | F2RL3 (0.57) | F2RL3 | |
| SCHEMBL19783091 | 0.80 | F2RL3 (0.57) | F2RL3 | |
| SCHEMBL19783413 | 0.80 | F2RL3 (0.71) | F2RL3ALDH1A1 | |
| SCHEMBL21379339 | 0.79 | F2RL3 (0.62) | F2RL3 | |
| SCHEMBL19783103 | 0.78 | F2RL3 (0.54) | F2RL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013774-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-01-18 | — | — | WO | disclosed |